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A quick algorithmic review on management of viral infectious diseases in pediatric solid organ transplant recipients
Front Pediatr. 2023 Sep 4;11:1252495. doi: 10.3389/fped.2023.1252495. eCollection 2023.ABSTRACTPediatric solid organ transplant is a life-saving procedure for children with end-stage organ failure. Viral infections are a common complication following pediatric solid organ transplantation (SOT), which can lead to increased morbidity and mortality. Pediatric solid organ transplant recipients are at an increased risk of viral infections due to their immunosuppressed state. The most commonly encountered viruses include cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus (HSV), varicella-zoster virus (VZV), ad...
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Marjan Moghadamnia Hamid Eshaghi Hosein Alimadadi Simin Dashti-Khavidaki Source Type: research

Effects of herpes zoster vaccination and antiviral treatment on the risk of stroke: a systematic review and meta-analysis
CONCLUSIONS: This meta-analysis suggests that the HZV, but not antiviral treatment, decreases the odds of developing stroke.PMID:37265460 | PMC:PMC10231675 | DOI:10.3389/fneur.2023.1176920
Source: Herpes - June 2, 2023 Category: Infectious Diseases Authors: Yong-Hui Jia Yu-Bo Dong Hai-Yin Jiang Ai-Juan Li Source Type: research

An Orally Administered Nonpathogenic Attenuated Vaccine Virus Can Be Used to Control SARS-CoV-2 Infection: A Complementary Plan B to COVID-19 Vaccination
Conclusions SIT has already been demonstrated to be safe and effective against five different families of viruses, hepatitis A virus, hepatitis B virus, hepatitis C virus, SARS-CoV-2, and herpes zoster virus. The R903/78 drug candidate is simple to manufacture and easy to administer in an outpatient setting. The expected cost of SIT will be affordable even in resource-limited countries.PMID:36176842 | PMC:PMC9511982 | DOI:10.7759/cureus.28467
Source: Herpes - September 30, 2022 Category: Infectious Diseases Authors: Tibor Bakacs Volker Sandig Imre Kovesdi Source Type: research

Acute herpes zoster radiculopathy mimicking cervical radiculopathy after ChAdOx1 nCoV-19/AZD1222 vaccination
This report aims to highlight the diagnostic dilemma between cervical radiculopathy secondary to spondylosis and zoster radiculopathy and how an erroneous diagnosis could result in inappropriate, aggressive surgical intervention and delayed treatment with antiviral therapy.PMID:35459652 | DOI:10.1136/bcr-2022-248943
Source: Herpes - April 23, 2022 Category: Infectious Diseases Authors: Andrew Dermawan Matthew Jun Min Ting Thomas Chemmanam Chok Lui Source Type: research

A standardized approach to the evaluation of antivirals against DNA viruses: Orthopox-, adeno-, and herpesviruses
Publication date: Available online 1 October 2018Source: Antiviral ResearchAuthor(s): Caroll B. Hartline, Kathy A. Keith, Jessica Eagar, Emma A. Harden, Terry L. Bowlin, Mark N. PrichardAbstractThe search for new compounds with a broad spectrum of antiviral activity is important and requires the evaluation of many compounds against several distinct viruses. Researchers attempting to develop new antiviral therapies for DNA virus infections currently use a variety of cell lines, assay conditions and measurement methods to determine in vitro drug efficacy, making it difficult to compare results from within the same laboratory...
Source: Antiviral Therapy - October 4, 2018 Category: Virology Source Type: research